P06396

Gelsolin plays a crucial role in regulating actin filament dynamics, which is essential for various cellular processes, including motility, shape maintenance, and intracellular transport. By severing actin filaments in the presence of calcium, Gelsolin facilitates cytoskeleton remodeling, allowing cells to respond effectively to environmental cues. This dynamic regulation is particularly important in leukocytes and platelets, where actin rearrangement is vital for immune responses and clot formation. Gelsolin′s ability to exist in both secreted and intracellular forms highlights its versatility and importance in maintaining cellular homeostasis.