Monoclonal Antibodies - AhR Mouse Monoclonal Antibody

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AhR Mouse Monoclonal Antibody

Catalog #：EAB22437

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22437-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	Dianost	Phone：+49 (0) 40 65472-053
	Bullenkoppel 11， 23896 Poggensee,	E-mail：ola@olasciences.com
Germany	Germany	Web：www.olasciences.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC, ELISA
Species Reactivity	Human, Mouse, Rat, Pig
Host / Isotype	Mouse IgG2b
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF/ICC=1:100-500　 FC=1:100-500
MW (kDa)	96
Conjugate	Unconjugate
Specificity	AhR Mouse Monoclonal Antibody detects endogenous levels of AhR protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Aryl hydrocarbon receptor; Ah Receptor; FVH3; RP85; bHLHe76; AHR
Gene Aliases	AHR
UniProt ID	P35869
Entrez Gene ID	196

Product Description

AhR is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. As a ligand-dependent transcription factor, AhR is essential for regulating the expression of genes involved in xenobiotic metabolism. Upon binding to TCDD or other ligands, AhR forms a complex with the Ah Receptor nuclear translocator (Arnt), facilitating its translocation to the nucleus where it binds to specific DNA sequences known as xenobiotic responsive elements (XREs). This interaction is vital for the transcriptional activation of genes that help detoxify harmful compounds, underscoring the importance of AhR in maintaining cellular homeostasis and responding to environmental stressors.

Product Image Gallery
Western blot analysis of extracts on HEK293, HepG2, CACO2 cells, using AhR Mouse Monoclonal Antibody (EAB22437) at 1:3000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol