Monoclonal Antibodies - TAK1 Mouse Monoclonal Antibody

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TAK1 Mouse Monoclonal Antibody

Catalog #：EAB22825

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22825-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, IHC-P, IF/ICC, FC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IHC-P=1:100-500　 IF/ICC=1:100-500　 FC=1:50-200
MW (kDa)	67
Conjugate	Unconjugate
Specificity	TAK1 Mouse Monoclonal Antibody detects endogenous levels of TAK1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Mitogen-activated protein kinase kinase kinase 7; CSCF; FMD2; TAK1; MEKK7; TGF1a; MAP3K7
Gene Aliases	MAP3K7
UniProt ID	O43318
Entrez Gene ID	6885

Product Description

TAK1 also known as is TGF1a, MAP3K7 is a member of the serine/threonine protein kinase family. TAK1 plays a pivotal role in mediating cellular responses to cytokines like TGFβ and interleukin-1 (IL-1) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, TAK1 forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2 activating downstream NF-κB and MAP kinase signaling pathways essential for inflammation, immune responses, cell survival, and apoptosis. Dysregulation of Tak1 function is associated with various pathological conditions, including cancer and inflammatory diseases, making Tak1 a critical target for biomedical research.

Product Image Gallery
Western blot analysis of extracts on K562, HEK293, NIH/3T3 cells, using TAK1 Mouse Monoclonal Antibody (EAB22825) at 1:2000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue, using TAK1 Mouse Monoclonal Antibody (EAB22825) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol