USA£º(540) 808-3925
China£º400-117-0038
Italy
Shopping Cart
Sign in \ Register
HSP27 Rabbit Monoclonal Antibody
Catalog #£ºEAB21246
  SKU-Pack Size Availability Size Price
EAB21246-100UL In Stock 100ul €297.70
If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com
Please select the country you are in to find your local distributor.
SBT BioChem Srl Phone£º+39 05 7156 8147
Via Ponte di Bagnolo, 811 Bologna, E-mail£ºinfo@sbtbiochem.it
Italy Italy Web£ºwww.sbtbiochem.it
Product Information
Applications WB, IHC-P, IF/ICC, FC
Species Reactivity Human, Mouse, Rat
Host / Isotype Rabbit IgG
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IP=1:10-100
IHC-P=1:50-200¡¡
IF/ICC=1:50-200¡¡
FC=1:10-100
MW (kDa) 27
Conjugate Unconjugate
Specificity HSP27 Rabbit Monoclonal Antibody detects endogenous levels of HSP27 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Heat shock protein family B (small) member 1; CMT2F; HMN2B; HMND3; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSPB1
Gene Aliases HSPB1
UniProt ID

P04792

Entrez Gene ID

3315

Product Description

HSP27 is a member of the heat shock protein family, functioning primarily as a molecular chaperone that assists in protein folding and protects cells from stress-induced damage. HSP27 is predominantly located in the cytoplasm but translocates to the nucleus under stress conditions, highlighting its role in cellular response mechanisms. HSP27′s ability to relocate allows for the regulation of various cellular processes, including apoptosis and cell survival, particularly in response to heat shock, cytokines, and hormonal signals. Notably, HSP27 undergoes extensive post-translational modifications, including phosphorylation, which enhances chaperone activity and is critical for protective functions during cellular stress. HSP27′s regulation by hormones like estrogen suggests a potential link to tumorigenesis in breast cancer, making HSP27 a valuable target for understanding cancer biology and developing therapeutic strategies. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Copyright 2015 EbioCell, Inc. All Rights Reserved. ¡¡±¸°¸ºÅ£º½òICP±¸2022005142ºÅ-1