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PSD95 Mouse Monoclonal Antibody
Catalog #£ºEAB22659
  SKU-Pack Size Availability Size Price
EAB22659-100UL In Stock 100ul €258.70
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Product Information
Applications WB, IHC-P, FC, ELISA
Species Reactivity Human, Mouse, Rat
Host / Isotype Mouse IgG1
Clonality Monoclonal
Applications Dilutions WB=1:500-2000¡¡
IHC-P=1:100-500¡¡
FC=1:50-200
MW (kDa) 80
Conjugate Unconjugate
Specificity PSD95 Mouse Monoclonal Antibody detects endogenous levels of PSD95 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) Discs large MAGUK scaffold protein 4; MRD62; PSD95; SAP90; SAP-90; DLG4
Gene Aliases DLG4
UniProt ID

P78352

Entrez Gene ID

1742

Product Description

PSD95 aslo known as SAP90, DLG4 is a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in synaptic signaling and plasticity by organizing and anchoring various proteins at the postsynaptic density of excitatory synapses. This localization is vital for proper synaptic functioning, as PSD-95 facilitates the clustering of receptors and signaling molecules, thereby influencing synaptic strength and communication between neurons. The structural integrity of PSD-95, characterized by PDZ, SH3, and guanylate kinase domains, allows interaction with various proteins, including NMDA and AMPA receptors, which are essential for synaptic transmission and plasticity. 

Product Image Gallery
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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