Monoclonal Antibodies - Progesterone Receptor/PR Mouse Monoclonal Antibody

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Progesterone Receptor/PR Mouse Monoclonal Antibody

Catalog #：EAB22591

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22591-100UL	In Stock	100ul	$298.50

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
United States	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IHC-P, FC, ELISA
Species Reactivity	Human, Mouse
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500　 FC=1:50-200
MW (kDa)	99
Conjugate	Unconjugate
Specificity	Progesterone Receptor/PR Mouse Monoclonal Antibody detects endogenous levels of PProgesterone Receptor/PR protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Progesterone receptor; PR; NR3C3; PGR
Gene Aliases	PGR
UniProt ID	P06401
Entrez Gene ID	5241

Product Description

PR(Progesterone Receptor) is a vital nuclear hormone receptor located within the cell nucleus, where PR functions as a transcription factor to regulate gene expression in response to progesterone binding. Nuclear localization is crucial for PR′s role in controlling essential biological processes such as the menstrual cycle, maintenance of pregnancy, and development of reproductive tissues. PR exists in two main isoforms, PR-A and PR-B, which are transcribed from distinct promoters and exhibit different functional properties. PR-B primarily acts as a transcriptional activator, promoting expression of genes involved in cell growth, differentiation, and apoptosis, while PR-A functions as a transcriptional repressor, modulating activity of other steroid hormone receptors.

Product Image Gallery
Western blot analysis of extracts on T47D, C2C12 cells, using Progesterone Receptor/PR Mouse Monoclonal Antibody (EAB22591) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue, using Progesterone Receptor/PR Mouse Monoclonal Antibody (EAB22591) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol