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PGC1¦Á Mouse Monoclonal antibody
Catalog #£ºEAB21937
  SKU-Pack Size Availability Size Price
EAB21937-100UL In Stock 100ul €336.70
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Dianost Phone£º+49 (0) 40 65472-053
Bullenkoppel 11£¬ 23896 Poggensee, E-mail£ºola@olasciences.com
Germany Germany Web£ºwww.olasciences.com
Product Information
Applications WB, IP, IHC-P, IF/ICC, ELISA
Species Reactivity Human, Mouse, Rat, Pig, Monkey
Host / Isotype Mouse IgG1
Clonality Monoclonal
Applications Dilutions WB=1:5000-20000¡¡
IP=1:200-1000
IHC-P=1:200-1000¡¡
IF/ICC=1:500-2000
MW (kDa) 91
Conjugate Unconjugate
Specificity PGC1¦Á Mouse Monoclonal antibody detects endogenous levels of PGC1¦Á protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20¡ãC least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4¡ãC for 1-2 weeks.
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Bioinformatics
Synonym(s) PPARG coactivator 1 alpha; LEM6; PGC1; PGC1A; PGC-1v; PPARGC1; PGC-1alpha; PGC-1(alpha); PGC-1¦Á; PPARGC1A
Gene Aliases PPARGC1A
UniProt ID

Q9UBK2

Entrez Gene ID

10891

Product Description

PGC1α also known as PGC1A, PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.  

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Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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