Recombinant Antibodies - Lamin B1 Rabbit Monoclonal Antibody

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Lamin B1 Rabbit Monoclonal Antibody

Catalog #：EAB21268

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21268-100UL	In Stock	100ul	€219.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:2000-10000　 IP=1:100-500 IHC-P=1:200-1000　 IF/ICC=1:200-1000
MW (kDa)	68
Conjugate	Unconjugate
Specificity	Lamin B1 Rabbit Monoclonal Antibody detects endogenous levels of Lamin B1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Lamin B1; LMN; ADLD; LMN2; LMNB; ADLDAT; MCPH26; LMNB1
Gene Aliases	LMNB1
UniProt ID	P20700
Entrez Gene ID	4001

Product Description

Lamin B1 also known as LMNB1 is one of the two B-type lamin proteins and is a component of the nuclear lamina. Lamin B1 plays a crucial role in maintaining the structural integrity of the nuclear envelope and is a key component of the nuclear lamina, which provides mechanical support to the nucleus and helps organize chromatin. Proper localization of Lamin B1 within the nucleus is essential for regulating gene expression and ensuring cellular stability, as disruptions in its function can lead to various diseases, including laminopathies and cancer. Additionally, Lamin B1 undergoes post-translational modifications such as farnesylation and phosphorylation, which are vital for its function and stability; increased phosphorylation of Lamin B1 is associated with the disintegration of the nuclear envelope during apoptosis, highlighting its importance in cellular processes.

Product Image Gallery
Western blot analysis of extracts on Hela, NIH/3T3, Mouse brain cells, using Lamin B1 Rabbit Monoclonal Antibody (EAB21268) at 1:5000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol