Recombinant Antibodies - FAP Rabbit Monoclonal Antibody

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FAP Rabbit Monoclonal Antibody

Catalog #：EAB22336

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22336-100UL	In Stock	100ul	$343.50

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	EbioCell	Phone：(540) 808-3925
	Imperial Business Park 4819 Emperor Boulevard,	E-mail：order@ebiocell.com
Canada	Suite 408 Durham, NC 27703, USA	Web：www.ebiocell.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC
Species Reactivity	Human
Host / Isotype	Rabbit IgG
Clonality	Monoclonal
Applications Dilutions	WB=1:1000-5000　 IP=1:10-100 IHC-P=1:100-500　 IF/ICC=1:100-500
MW (kDa)	87
Conjugate	Unconjugate
Specificity	FAP Rabbit Monoclonal Antibody detects endogenous levels of FAP protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Fibroblast activation protein alpha; FAPA; SIMP; DPPIV; FAPalpha; FAP
Gene Aliases	FAP
UniProt ID	Q12884
Entrez Gene ID	2191

Product Description

FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. FAP is essential for remodeling developing tissues, highlighting FAP′s importance in both normal and pathological processes. Structurally, FAP is an integral membrane gelatinase composed of N-glycosylated, proteolytically inactive subunits, which underscores unique functional properties. FAP expression on chondrocyte membranes is upregulated by cytokines interleukin-1 and oncostatin M, and increases in patients with osteoarthritis. This expression is co-localized with matrix metalloproteinases MMP-1 and MMP-13, as well as CD44 variants v3 and v7/8, indicating involvement in complex cellular interactions.

Product Image Gallery
Western blot analysis of extracts on U87MG, Mouse skin cells, using FAP Rabbit Monoclonal Antibody (EAB22336) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol