Monoclonal Antibodies - Exportin-1/CRM1 Mouse Monoclonal Antibody

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Exportin-1/CRM1 Mouse Monoclonal Antibody

Catalog #：EAB22173

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22173-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

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	OlaSciences	Phone：+33 (0) 9 77 4001 556
	87, rue des Suisses 65000 Nanterre,	E-mail：ola@olasciences.com
France	France	Web：www.olasciences.com

Product Information
Applications	WB, IP, IHC-P, IF/ICC, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:2000-10000　 IP=1:100-500 IHC-P=1:200-1000　 IF/ICC=1:100-500
MW (kDa)	123
Conjugate	Unconjugate
Specificity	Exportin-1/CRM1 Mouse Monoclonal Antibody detects endogenous levels of Exportin-1/CRM1 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Exportin 1; emb; CRM1; exp1; CRM-1; XPO1
Gene Aliases	XPO1
UniProt ID	O14980
Entrez Gene ID	7514

Product Description

CRM1 also known as Exportin-1, XPO1 is a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. CRM1 plays a crucial role in nuclear export of proteins and RNA, particularly those containing a nuclear export signal (NES). CRM1′s function is vital for maintaining cellular homeostasis and regulating gene expression, as CRM1 facilitates transport of essential molecules out of the nucleus, thereby influencing various cellular processes such as signal transduction and stress responses. CRM1′s interaction with specific leucine-rich proteins underscores its importance in selective export mechanism, which is essential for proper cellular function.

Product Image Gallery
Western blot analysis of extracts on Hela, HepG2, Raw264.7, NIH/3T3 cells, using Exportin-1/CRM1 Mouse Monoclonal Antibody (EAB22173) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Predicted band size: 123 kDa; Observed band size: 100-110 kDa

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol