Monoclonal Antibodies - Cdc25A Mouse Monoclonal Antibody

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Cdc25A Mouse Monoclonal Antibody

Catalog #：EAB21759

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB21759-100UL	In Stock	100ul	€336.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Betaclonal	Phone：+34 (0)91 471 6763
	29/1 Lomonosovsky Pr,	E-mail：tech@betaclonal.com
Spain	Madrid, Spain	Web：www.betaclonal.com

Product Information
Applications	WB, ELISA
Species Reactivity	Human, Mouse, Rat
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:5000-20000
MW (kDa)	59
Conjugate	Unconjugate
Specificity	Cdc25A Mouse Monoclonal Antibody detects endogenous levels of Cdc25A protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Cell division cycle 25A; CDC25A2; CDC25A
Gene Aliases	CDC25A
UniProt ID	P30304
Entrez Gene ID	993

Product Description

CDC25A is a member of the CDC25 family of phosphatases. Cdc25A plays a crucial role in cell cycle regulation, particularly in the transition from G2 phase to mitosis, by acting as a phosphatase that dephosphorylates and activates the cyclin-dependent kinase Cdc2. This activation is essential for the proper progression of mitosis, as it allows the cell to enter the mitotic phase and ensures accurate chromosome segregation. Dysregulation of Cdc25A can lead to uncontrolled cell division and has been implicated in various cancers, making Cdc25A a significant target for therapeutic intervention. Cdc25A is primarily located in the nucleus, where Cdc25A interacts with other cell cycle regulators, and Cdc25A activity is tightly controlled by phosphorylation and dephosphorylation events.

Product Image Gallery
Western blot analysis of extracts on Hela, Jurkat, 4T1 cells, using Cdc25A Mouse Monoclonal Antibody (EAB21759) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol