P10809

HSP60 also known as HSPD1 is a key member of the heat shock protein family. HSP60 plays a crucial role in mitochondrial function, acting as a molecular chaperone that assists in proper folding and assembly of newly synthesized proteins destined for the mitochondrial matrix. HSP60 is essential for maintaining cellular homeostasis, particularly under stress conditions, as HSP60 helps prevent aggregation of misfolded proteins, which can lead to cellular dysfunction and disease. HSP60 is located in both mitochondria and cytosol, highlighting HSP60′s importance in cellular processes that require transport and proper folding of polypeptides across membranes. HSP60′s ability to interact with various client proteins underscores HSP60′s significance in cellular stress responses and potential as a therapeutic target in diseases associated with protein misfolding.