P61158

ARP3 also known as ACTR3 is a crucial component of the ARP2/3 complex, which plays a vital role in actin polymerization, a process essential for various cellular functions including cell migration, adhesion, and the formation of cellular protrusions. The ARP2/3 complex facilitates the nucleation of new actin filaments, enabling the rapid reorganization of the cytoskeleton in response to extracellular signals. This dynamic restructuring is particularly important in processes such as chemotaxis, where cells must move toward chemical signals, and in the formation of lamellipodia and filopodia, which are critical for cell movement and shape changes. The interaction of ARP3 with other proteins, such as the WASP family, is essential for the activation of the ARP2/3 complex, highlighting ARP3′s role in linking signaling pathways to cytoskeletal dynamics.