MAP2(Microtubule associated protein 2) is a protein that belongs to the microtubule-associated protein family. MAP2 plays a crucial role in the stabilization and assembly of microtubules, which are essential components of the cytoskeletal network that provide structural support and shape to cells. MAP2 is primarily located in neuronal cell bodies and dendrites, where MAP-2 is vital for maintaining the integrity of the neuronal cytoskeleton and facilitating intracellular transport. MAP2 is particularly important in neuronal development and plasticity, as MAP2 influences the morphology of dendritic spines and synaptic connections. Dysregulation of MAP2 has been associated with various neurodegenerative diseases, highlighting MAP2′s significance in maintaining neuronal health.