Monoclonal Antibodies - IMP3 Mouse Monoclonal Antibody

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IMP3 Mouse Monoclonal Antibody

Catalog #：EAB22053

Datasheet

	SKU-Pack Size	Availability	Size	Price
	EAB22053-100UL	In Stock	100ul	€258.70

If you want to get a larger packsize, Please contact your local distributor or
email us at info@ebiocell.com

Please select the country you are in to find your local distributor.

	Cambiotech	Phone：+44 (0) 188 448801
	Lanwades Business Park,	E-mail：info@cambiotech.com
Ireland	Kobenhavn K, Ireland	Web：www.cambiotech.com

Product Information
Applications	WB, IHC-P, ELISA
Species Reactivity	Human
Host / Isotype	Mouse IgG1
Clonality	Monoclonal
Applications Dilutions	WB=1:500-2000　 IHC-P=1:100-500
MW (kDa)	64
Conjugate	Unconjugate
Specificity	IMP3 Mouse Monoclonal Antibody detects endogenous levels of IMP3 protein.
Purification	Affinity purification
Concentration	1mg/ml
Format	Liquid
Formulation	In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping	Gel Pack
Storage	Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
Research Use	For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Bioinformatics
Synonym(s)	Insulin like growth factor 2 mRNA binding protein 3; KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3; IGF2BP3
Gene Aliases	IGF2BP3
UniProt ID	O00425
Entrez Gene ID	10643

Product Description

IMP3 also kwnon as MRPS4, IGF2BP3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. IMP3 protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. Proper functioning of Imp3 is vital for ribosome biogenesis, a process fundamental for protein synthesis in all living cells. Disruptions in ribosomal processing can lead to various cellular dysfunctions and are implicated in several diseases, including cancer and genetic disorders.

Product Image Gallery
Western blot analysis of extracts on Jurkat, K562 cells, using IMP3 Mouse Monoclonal Antibody (EAB22053) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution. Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue, using IMP3 Mouse Monoclonal Antibody (EAB22053) at 1:200 dilution.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol