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Raloxifene hydrochloride (CAS: 82640-04-8)
Catalog #:EBC51158
  SKU-Pack Size Availability Size Price
EBC51158-1ML In Stock 1mL(10mM in DMSO) ¥390.00
EBC51158-10MG In Stock 10mg ¥390.00
EBC51158-50MG In Stock 50mg ¥490.00
EBC51158-100MG In Stock 100mg ¥790.00
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Product Information
Synonym(s) Raloxifene HCl, Keoxifene
Chemical Name [6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone hydrochloride
Application Raloxifene hydrochloride is a SERM of ERα and ERβ
CAS Number 82640-04-8
Purity ≥98%
Molecular Weight 510.04
Molecular Formula C₂₈H₂₇NO₄S•HCl
Target & IC50 ER α: IC50 = 0.72 nM
ER β: IC50 = 43 nM
MCF7: IC50 = 0.2 nM
Solubility DMSO: 25.5 mg/mL (50 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 1.9606 ml 9.8032 ml 19.6063 ml
5 mM 0.3921 ml 1.9606 ml 3.9213 ml
10 mM 0.1961 ml 0.9803 ml 1.9606 ml
50 mM 0.0392 ml 0.1961 ml 0.3921 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Raloxifene hydrochloride is a selective estrogen receptor modulator (SERM), binding to ERα and ERβ. Tissue-dependently blocks or activates estrogen-induced transcription. Exhibits estrogen agonist behavior in bone but acts as an anti-estrogen in breast and uterine tissue. Raloxifene hydrochloride exhibits inhibitory effects of progesterone receptor induction by estrogen in D12 rat hypothalamic cells. Raloxifene hydrochloride is a substrate of Estrogen Receptor. 

Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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