|Please select the country you are in to find your local distributor.
|WB, IP, IHC-P, IF/ICC, FC
|Human, Mouse, Rat, Monkey, Dog, Pig, Bovine, Chicken
|Host / Isotype
|COX IV Rabbit Monoclonal Antibody detects endogenous levels of COX IV protein.
|In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
|Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
|For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|MC4DN16; COX IV-1; AL024441; COX-4; COX 4; COX IV-1; COX4; COX4-1; Cox4a; COX4I1; COXIV; COXIV-1; IV-1; COXIV;
|Entrez Gene ID
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms.
|Product Image Gallery
Western blot analysis of extracts on different cells, using COX IV Rabbit Monoclonal Antibody (EAB21222) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Lane3: Pig Heart